Adverse reactions associated with a Fuenzalida-Palacios rabies vaccine: a quasi-experimental study
The Fuenzalida-Palacios rabies vaccine has been used in South America for rabies post-exposure prophylaxis. To determine the frequency of adverse reactions associated with this vaccine compared to a control group a quasi-experimental study was carried out in Uberlândia, Brazil, from May 1997 to April 1998. Victims of bites or other injuries by dogs or other mammals and who received or not post-exposure prophylaxis with Fuenzalida-Palacios rabies vaccine were compared as to the occurrence of a list of signs and symptoms. Out of 2,440 victims of bites and other injuries from dogs and other mammals 2,114 participated in the study; 1,004 of them provided follow-up information within 10 to 15 days. Headache and pain at the injection sites were the most commonly found symptoms (125/1,000). No neuroparalytic event was detected. Patients who were given Fuenzalida-Palacios rabies vaccine and those who were not had similar incidences of symptoms (risk ratios close to 1). Regarding the occurrence of adverse reactions, Fuenzalida-Palacios rabies vaccine is a valid alternative for rabies post-exposure prophylaxis.
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Sociedade Brasileira de Medicina Tropical - SBMT
2004
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oai:scielo:S0037-868220040001000022004-03-19Adverse reactions associated with a Fuenzalida-Palacios rabies vaccine: a quasi-experimental studyBonito,Rosuita FratariOliveira,Neide Mattar deNishioka,Sérgio de Andrade Adverse reaction Fuenzalida-Palacios vaccine Post-exposure prophylaxis Quasi-experimental study Rabies vaccine The Fuenzalida-Palacios rabies vaccine has been used in South America for rabies post-exposure prophylaxis. To determine the frequency of adverse reactions associated with this vaccine compared to a control group a quasi-experimental study was carried out in Uberlândia, Brazil, from May 1997 to April 1998. Victims of bites or other injuries by dogs or other mammals and who received or not post-exposure prophylaxis with Fuenzalida-Palacios rabies vaccine were compared as to the occurrence of a list of signs and symptoms. Out of 2,440 victims of bites and other injuries from dogs and other mammals 2,114 participated in the study; 1,004 of them provided follow-up information within 10 to 15 days. Headache and pain at the injection sites were the most commonly found symptoms (125/1,000). No neuroparalytic event was detected. Patients who were given Fuenzalida-Palacios rabies vaccine and those who were not had similar incidences of symptoms (risk ratios close to 1). Regarding the occurrence of adverse reactions, Fuenzalida-Palacios rabies vaccine is a valid alternative for rabies post-exposure prophylaxis.info:eu-repo/semantics/openAccessSociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical v.37 n.1 20042004-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822004000100002en10.1590/S0037-86822004000100002 |
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Bonito,Rosuita Fratari Oliveira,Neide Mattar de Nishioka,Sérgio de Andrade |
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Bonito,Rosuita Fratari Oliveira,Neide Mattar de Nishioka,Sérgio de Andrade Adverse reactions associated with a Fuenzalida-Palacios rabies vaccine: a quasi-experimental study |
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Bonito,Rosuita Fratari Oliveira,Neide Mattar de Nishioka,Sérgio de Andrade |
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Bonito,Rosuita Fratari |
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Adverse reactions associated with a Fuenzalida-Palacios rabies vaccine: a quasi-experimental study |
title_short |
Adverse reactions associated with a Fuenzalida-Palacios rabies vaccine: a quasi-experimental study |
title_full |
Adverse reactions associated with a Fuenzalida-Palacios rabies vaccine: a quasi-experimental study |
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Adverse reactions associated with a Fuenzalida-Palacios rabies vaccine: a quasi-experimental study |
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Adverse reactions associated with a Fuenzalida-Palacios rabies vaccine: a quasi-experimental study |
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adverse reactions associated with a fuenzalida-palacios rabies vaccine: a quasi-experimental study |
description |
The Fuenzalida-Palacios rabies vaccine has been used in South America for rabies post-exposure prophylaxis. To determine the frequency of adverse reactions associated with this vaccine compared to a control group a quasi-experimental study was carried out in Uberlândia, Brazil, from May 1997 to April 1998. Victims of bites or other injuries by dogs or other mammals and who received or not post-exposure prophylaxis with Fuenzalida-Palacios rabies vaccine were compared as to the occurrence of a list of signs and symptoms. Out of 2,440 victims of bites and other injuries from dogs and other mammals 2,114 participated in the study; 1,004 of them provided follow-up information within 10 to 15 days. Headache and pain at the injection sites were the most commonly found symptoms (125/1,000). No neuroparalytic event was detected. Patients who were given Fuenzalida-Palacios rabies vaccine and those who were not had similar incidences of symptoms (risk ratios close to 1). Regarding the occurrence of adverse reactions, Fuenzalida-Palacios rabies vaccine is a valid alternative for rabies post-exposure prophylaxis. |
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Sociedade Brasileira de Medicina Tropical - SBMT |
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2004 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822004000100002 |
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