Assessment of the plan for pre-exposition vaccination with Fuenzalida-Palacios anti-rabies vaccine
Studies ere carried out to monitor the titres of anti-rabies antibodies taken from individuals exposed to the risk of infection. Fifty-seven individuals aged between 20 and 40, were vaccinated with a minimum titre of 1.3 IU Fuenzalida-Palacios type anti-rabies vaccine. The vaccination plan consisted of the application of three doses at two day intervals and a booster applied 28 days after the final dose. The accompainment of the antibody titres was achieved by means of the seroneutralization test over a total period of 18 months. Through the monitoring carried out, it was found to be necessary to apply a booster vaccination to part of the group. Some of these individuals were revaccinated with Fuenzalida-Palacios type vaccine with a minimum titre of 1.3 IU. And some with cellular vaccine with a minimum titre of 2.5 IU. All the individuals responded with titres greater than 0.5 IU, maintaining these levels until the end of the observation period, demonstrating a ready anamnestic response to both immunogens.
| Main Authors: | , , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Instituto de Tecnologia do Paraná - Tecpar
2000
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| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132000000300002 |
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