Characterization and storage stability of spray dried soy-rapeseed lecithin/trehalose liposomes loaded with a tilapia viscera hydrolysate
Drying-induced stabilization is a challenge that delivery systems still face. This study aims to investigate the effects of adding trehalose to spray dried soy-rapeseed lecithin liposomes, and the storage stability of the dried liposomes loaded with a tilapia viscera protein hydrolysate, during 42 days at 4 °C and 23 °C, and at different relative humidity (RH). Particle size increased from 215 to 250 nm in fresh liposomes to 258–314 nm after spray drying according to trehalose concentration, all preparations showing a strong electronegative ζ Potential (−48.5 to −59.9 mV). Dried liposomes stored at 4 °C maintained lower polydispersity and higher solubility than those stored at 23 °C. Changes in water activity (Aw), FTIR and DSC revealed structural changes in samples stored at 23 °C and high RH. Spray dried hydrolysate-containing liposomes could be considered as a functional food ingredient due to the substantial antioxidant activity and angiotensin-converting enzyme (ACE) inhibitory capacity after in vitro simulated gastrointestinal digestion.
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Language: | English |
| Published: |
Elsevier
2021
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| Subjects: | Lecithin liposomes, Spray-drying, Trehalose, Fish hydrolysate, Storage stability, In vitro gastrointestinal digestion, |
| Online Access: | http://hdl.handle.net/10261/251171 http://dx.doi.org/10.13039/501100011033 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100005278 |
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