Chiral separation of amino acids derivatised with fluorescein isothiocyanate by single isomer derivatives 3-monodeoxy-3-monoamino-β- and γ-cyclodextrins: the effect of the cavity size
Thirteen enantiomeric pairs of α-amino acids derivatised with fluorescein isothiocyanate (FITC-AAs) were separated in capillary electrophoresis (CE) using as chiral selectors the single isomer derivatives (SIDs) 3-monodeoxy-3-monoamino-β- and γ-cyclodextrins. The chiral separation data obtained by these strictly homologous compounds, show different behaviours, allowing to hypothesise a possible structure of the obtained selector-analyte complexes, as well as highlighting the crucial role of the cavity size and the significant effects on the resolution obtained by small differences in the structural characteristics of these analytes. © 2012 Elsevier B.V.
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | artículo biblioteca |
| Published: |
Elsevier
2012
|
| Subjects: | Capillary electrophoresis, Amino acids, Molecular recognition, Chiral separation, Cyclodextrin derivatives, |
| Online Access: | http://hdl.handle.net/10261/101262 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|