Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells.
Skin cancer is the most common type of malignancy in light-skinned populations and phenolics are promising anticarcinogenic agents.To characterise and evaluate the protective potential of apple extracts against the DNA damage caused by UV-radiation in culture of human fibroblasts as well as to verify the anticarcinogenic effect of these extracts in murine and human melanoma cells.
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Main Authors: | , , , , , , , , , , , |
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Format: | Artigo de periódico biblioteca |
Language: | Ingles English |
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2021-11-19
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Subjects: | Maçã, Câncer, DNA, |
Online Access: | http://www.alice.cnptia.embrapa.br/alice/handle/doc/1136345 https://doi.org/10.1016/j.phyplu.2021.100112 |
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dig-alice-doc-11363452021-11-19T15:00:34Z Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells. RAPHAELLI, C. de O. AZEVEDO, J. G. PEREIRA, E. dos S. VINHOLES, J. R. CAMARGO, T. M. HOFFMANN, J. F. RIBEIRO, J. A. VIZZOTTO, M. ROMBALDI, C. V. WINK, M. R. BRAGANHOL, E. NORA, L. CHIRLE DE OLIVEIRA RAPHAELLI, UFPel; JÉSSICA GONÇALVES AZEVEDO; ELISA DOS SANTOS PEREIRA; JULIANA ROCHA VINHOLES; TAIANE MOTA CAMARGO; JESSICA FERNANDA HOFFMANN; JARDEL ARAÚJO RIBEIRO; MARCIA VIZZOTTO, CPACT; CÉSAR VALMOR ROMBALDI, UFPel; MÁRCIA ROSÂNGELA WINK; ELIZANDRA BRAGANHOL; LEONARDO NORA. Maçã Câncer DNA Skin cancer is the most common type of malignancy in light-skinned populations and phenolics are promising anticarcinogenic agents.To characterise and evaluate the protective potential of apple extracts against the DNA damage caused by UV-radiation in culture of human fibroblasts as well as to verify the anticarcinogenic effect of these extracts in murine and human melanoma cells. 2021-11-19T15:00:24Z 2021-11-19T15:00:24Z 2021-11-19 2021 Artigo de periódico Phytomedicine Plus, v. 1, n. 4, 100112, Nov. 2021. http://www.alice.cnptia.embrapa.br/alice/handle/doc/1136345 https://doi.org/10.1016/j.phyplu.2021.100112 Ingles en openAccess |
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Maçã Câncer DNA Maçã Câncer DNA |
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Maçã Câncer DNA Maçã Câncer DNA RAPHAELLI, C. de O. AZEVEDO, J. G. PEREIRA, E. dos S. VINHOLES, J. R. CAMARGO, T. M. HOFFMANN, J. F. RIBEIRO, J. A. VIZZOTTO, M. ROMBALDI, C. V. WINK, M. R. BRAGANHOL, E. NORA, L. Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells. |
description |
Skin cancer is the most common type of malignancy in light-skinned populations and phenolics are promising anticarcinogenic agents.To characterise and evaluate the protective potential of apple extracts against the DNA damage caused by UV-radiation in culture of human fibroblasts as well as to verify the anticarcinogenic effect of these extracts in murine and human melanoma cells. |
author2 |
CHIRLE DE OLIVEIRA RAPHAELLI, UFPel; JÉSSICA GONÇALVES AZEVEDO; ELISA DOS SANTOS PEREIRA; JULIANA ROCHA VINHOLES; TAIANE MOTA CAMARGO; JESSICA FERNANDA HOFFMANN; JARDEL ARAÚJO RIBEIRO; MARCIA VIZZOTTO, CPACT; CÉSAR VALMOR ROMBALDI, UFPel; MÁRCIA ROSÂNGELA WINK; ELIZANDRA BRAGANHOL; LEONARDO NORA. |
author_facet |
CHIRLE DE OLIVEIRA RAPHAELLI, UFPel; JÉSSICA GONÇALVES AZEVEDO; ELISA DOS SANTOS PEREIRA; JULIANA ROCHA VINHOLES; TAIANE MOTA CAMARGO; JESSICA FERNANDA HOFFMANN; JARDEL ARAÚJO RIBEIRO; MARCIA VIZZOTTO, CPACT; CÉSAR VALMOR ROMBALDI, UFPel; MÁRCIA ROSÂNGELA WINK; ELIZANDRA BRAGANHOL; LEONARDO NORA. RAPHAELLI, C. de O. AZEVEDO, J. G. PEREIRA, E. dos S. VINHOLES, J. R. CAMARGO, T. M. HOFFMANN, J. F. RIBEIRO, J. A. VIZZOTTO, M. ROMBALDI, C. V. WINK, M. R. BRAGANHOL, E. NORA, L. |
format |
Artigo de periódico |
topic_facet |
Maçã Câncer DNA |
author |
RAPHAELLI, C. de O. AZEVEDO, J. G. PEREIRA, E. dos S. VINHOLES, J. R. CAMARGO, T. M. HOFFMANN, J. F. RIBEIRO, J. A. VIZZOTTO, M. ROMBALDI, C. V. WINK, M. R. BRAGANHOL, E. NORA, L. |
author_sort |
RAPHAELLI, C. de O. |
title |
Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells. |
title_short |
Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells. |
title_full |
Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells. |
title_fullStr |
Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells. |
title_full_unstemmed |
Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells. |
title_sort |
phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells. |
publishDate |
2021-11-19 |
url |
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1136345 https://doi.org/10.1016/j.phyplu.2021.100112 |
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