Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells.

Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells.

Skin cancer is the most common type of malignancy in light-skinned populations and phenolics are promising anticarcinogenic agents.To characterise and evaluate the protective potential of apple extracts against the DNA damage caused by UV-radiation in culture of human fibroblasts as well as to verify the anticarcinogenic effect of these extracts in murine and human melanoma cells.

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Bibliographic Details
Main Authors: RAPHAELLI, C. de O., AZEVEDO, J. G., PEREIRA, E. dos S., VINHOLES, J. R., CAMARGO, T. M., HOFFMANN, J. F., RIBEIRO, J. A., VIZZOTTO, M., ROMBALDI, C. V., WINK, M. R., BRAGANHOL, E., NORA, L.
Other Authors: CHIRLE DE OLIVEIRA RAPHAELLI, UFPel; JÉSSICA GONÇALVES AZEVEDO; ELISA DOS SANTOS PEREIRA; JULIANA ROCHA VINHOLES; TAIANE MOTA CAMARGO; JESSICA FERNANDA HOFFMANN; JARDEL ARAÚJO RIBEIRO; MARCIA VIZZOTTO, CPACT; CÉSAR VALMOR ROMBALDI, UFPel; MÁRCIA ROSÂNGELA WINK; ELIZANDRA BRAGANHOL; LEONARDO NORA.
Format: Artigo de periódico biblioteca
Language:Ingles
English
Published: 2021-11-19
Subjects:Maçã, Câncer, DNA,
Online Access:http://www.alice.cnptia.embrapa.br/alice/handle/doc/1136345
https://doi.org/10.1016/j.phyplu.2021.100112
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Internet

http://www.alice.cnptia.embrapa.br/alice/handle/doc/1136345
https://doi.org/10.1016/j.phyplu.2021.100112

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