Simultaneous quantification of oxidative stress and cell spreading using 5-(and-6)-chloromethyl-2′,7′-dichlorofluorescein

by Koopman, Werner J.H., Verkaart, Sjoerd, Van Emst-De Vries, Sjenet E., Grefte, Sander, Smeitink, Jan A.M., Willems, Peter H.G.M.

R-Ras alters Ca2+ homeostasis by increasing the Ca2+ leak across the endoplasmic reticular membrane

by Koopman, Werner J.H., Bosch, Remko R., Van Emst-De Vries, Sjenet E., Spaargaren, Marcel, De Pont, Jan Joep H.H.M., Willems, Peter H.G.M.

Mitigation of NADH : Ubiquinone oxidoreductase deficiency by chronic Trolox treatment

by Koopman, Werner J.H., Verkaart, Sjoerd, van Emst-de Vries, Sjenet E., Grefte, Sander, Smeitink, Jan A.M., Nijtmans, Leo G.J., Willems, Peter H.G.M.

Mitochondrial and cytosolic thiol redox state are not detectably altered in isolated human NADH:ubiquinone oxidoreductase deficiency

by Verkaart, Sjoerd, Koopman, Werner J.H., Cheek, Julia, van Emst-de Vries, Sjenet E., van den Heuvel, Lambertus W.P.J., Smeitink, Jan A.M., Willems, Peter H.G.M.

Decreased agonist-stimulated mitochondrial ATP production caused by a pathological reduction in endoplasmic reticulum calcium content in human complex I deficiency

by Visch, Henk Jan, Koopman, Werner J.H., Leusink, Anouk, Van Emst-De Vries, Sjenet E., Van Den Heuvel, Lambertus W.P.J., Willems, Peter H.G.M., Smeitink, Jan A.M.

Superoxide production is inversely related to complex I activity in inherited complex I deficiency

by Verkaart, Sjoerd, Koopman, Werner J.H., van Emst-de Vries, Sjenet E., Nijtmans, Leo G.J., van den Heuvel, Lambertus W.P.J., Smeitink, Jan A.M., Willems, Peter H.G.M.

Quantifying small molecule phenotypic effects using mitochondrial morpho-functional fingerprinting and machine learning

by Blanchet, Lionel, Smeitink, Jan A.M., Van Emst - De Vries, Sjenet E., Vogels, Caroline, Pellegrini, Mina, Jonckheere, An I., Rodenburg, Richard J.T., Buydens, Lutgarde M.C., Beyrath, Julien, Willems, Peter H.G.M., Koopman, Werner J.H.

Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells

by Basit, Farhan, Van Oppen, Lisanne M.P.E., Schöckel, Laura, Bossenbroek, Hasse M., Van Emst-de Vries, Sjenet E., Hermeling, Johannes C.W., Grefte, Sander, Kopitz, Charlotte, Heroult, Melanie, Willems, Peter H.G.M., Koopman, W.J.H.

Biodegradable Synthetic Organelles Demonstrate ROS Shielding in Human-Complex-I-Deficient Fibroblasts

by Van Oppen, Lisanne M.P.E., Abdelmohsen, Loai K.E.A., Van Emst-De Vries, Sjenet E., Welzen, Pascal L.W., Wilson, Daniela A., Smeitink, Jan A.M., Koopman, Werner J.H., Brock, Roland, Willems, Peter H.G.M., Williams, David S., Van Hest, Jan C.M.

NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients : A stabilizing role for NDUFAF2

by Adjobo-Hermans, Merel J.W., de Haas, Ria, Willems, Peter H.G.M., Wojtala, Aleksandra, van Emst-de Vries, Sjenet E., Wagenaars, Jori A., van den Brand, Mariel, Rodenburg, Richard J., Smeitink, Jan A.M., Nijtmans, Leo G., Sazanov, Leonid A., Wieckowski, Mariusz R., Koopman, Werner J.H.

The decylTPP mitochondria-targeting moiety lowers electron transport chain supercomplex levels in primary human skin fibroblasts

by Bulthuis, Elianne P., Einer, Claudia, Distelmaier, Felix, Groh, Laszlo, van Emst - de Vries, Sjenet E., van de Westerlo, Els, van de Wal, Melissa, Wagenaars, Jori, Rodenburg, Richard J., Smeitink, Jan A.M., Riksen, Niels P., Willems, Peter H.G.M., Adjobo-Hermans, Merel J.W., Zischka, Hans, Koopman, Werner J.H.

Metabolic consequences of NDUFS4 gene deletion in immortalized mouse embryonic fibroblasts

by Valsecchi, Federica, Monge, Claire, Forkink, Marleen, De Groof, Ad J.C., Benard, Giovanni, Rossignol, Rodrigue, Swarts, Herman G., Van Emst-De Vries, Sjenet E., Rodenburg, Richard J., Calvaruso, Maria A., Nijtmans, Leo G.J., Heeman, Bavo, Roestenberg, Peggy, Wieringa, Be, Smeitink, Jan A.M., Koopman, Werner J.H., Willems, Peter H.G.M.