Live-imaging readouts and cell models for phenotypic profiling of mitochondrial function

by Iannetti, Eligio F., Prigione, Alessandro, Smeitink, Jan A.M., Koopman, Werner J.H., Beyrath, Julien, Renkema, Herma

Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD+

by Iannetti, Eligio F., Smeitink, Jan A.M., Willems, Peter H.G.M., Beyrath, Julien, Koopman, Werner J.H.

Mitochondrial disorders in children : Toward development of small-molecule treatment strategies

by Koopman, Werner J.H., Beyrath, Julien, Fung, Cheuk Wing, Koene, Saskia, Rodenburg, Richard J., Willems, Peter H.G.M., Smeitink, Jan A.M.

Quantifying small molecule phenotypic effects using mitochondrial morpho-functional fingerprinting and machine learning

by Blanchet, Lionel, Smeitink, Jan A.M., Van Emst - De Vries, Sjenet E., Vogels, Caroline, Pellegrini, Mina, Jonckheere, An I., Rodenburg, Richard J.T., Buydens, Lutgarde M.C., Beyrath, Julien, Willems, Peter H.G.M., Koopman, Werner J.H.

Stimulation of cholesterol biosynthesis in mitochondrial complex I-deficiency lowers reductive stress and improves motor function and survival in mice

by Schirris, Tom J.J., Rossell, Sergio, de Haas, Ria, Frambach, Sanne J.C.M., Hoogstraten, Charlotte A., Renkema, Herma, Beyrath, Julien D., Willems, Peter H.G.M., Huynen, Martijn A., Smeitink, Jan A.M., Russel, Frans G.M., Notebaart, Richard A.

SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans

by Krabbendam, Inge E., Honrath, Birgit, Dilberger, Benjamin, Iannetti, Eligio F., Branicky, Robyn S., Meyer, Tammo, Evers, Bernard, Dekker, Frank J., Koopman, Werner J.H., Beyrath, Julien, Bano, Daniele, Schmidt, Martina, Bakker, Barbara M., Hekimi, Siegfried, Culmsee, Carsten, Eckert, Gunter P., Dolga, Amalia M.

Statin-induced myopathy is associated with mitochondrial complex III inhibition

by Schirris, Tom J.J., Renkema, Herma, Ritschel, Tina, Voermans, Nicol C., Bilos, Albert, Van Engelen, Baziel G.M., Brandt, Ulrich, Koopman, Werner J.H., Beyrath, Julien D., Rodenburg, Richard J., Willems, Peter H.G.M., Smeitink, Jan A.M., Russel, Frans G.M.