Argonaute bypasses cellular obstacles without hindrance during target search

by Cui, Tao Ju, Klein, Misha, Hegge, Jorrit W., Chandradoss, Stanley D., van der Oost, John, Depken, Martin, Joo, Chirlmin

Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a

by Olivi, Lorenzo, Bagchus, Cleo, Pool, Victor, Bekkering, Ezra, Speckner, Konstantin, Offerhaus, Hidde, Wu, Wen Y., Depken, Martin, Martens, Koen, Staals, Raymond, Hohlbein, Johannes

Cas3-Derived Target DNA Degradation Fragments Fuel Primed CRISPR Adaptation

by Künne, Tim, Kieper, Sebastian N., Bannenberg, Jasper W., Vogel, Anne, Miellet, Willem R., Klein, Misha, Depken, Martin, Suarez-Diez, Maria, Brouns, Stan J.J.

CRISPR Cas3 Plasmid degradation assays

by Kunne, T.A., Kieper, Sebastian, Bannenberg, J.W., Vogel, A.I.M., Miellet, Willem, Klein, Misha, Depken, Martin, Suarez Diez, M., Brouns, S.J.J.