Metastatic jejunal neuroendocrine tumor to the breast: Case report and literature review

Abstract Neuroendocrine tumors (NETs) are the most prevalent neoplasm of the small bowel; these present a diagnostic challenge because of their low prevalence and non-specific clinical manifestations. Breast metastasis is rare. We present the case of a 55-year-old female with a painful nodule in the right breast. Mammography reported a solid mass, BBIRADS 4C, with no axillary lymph nodes. Biopsy reported infiltrating ductal carcinoma. Conservative surgery was performed. Histopathology findings are compatible with a well-differentiated (G2) metastatic NET with a gastrointestinal primary. Ga. DOTANOC positron emission tomography/computed tomography scan showed proximal jejunum diffuse mucosal thickening with two foci of increased radiotracer uptake with adjacent adenopathies.

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Bibliographic Details
Main Authors: Fernández-Christlien,Gonzalo, Rivera-García-Granados,Ana, Kajomovitz-Bialostozky,Daniel
Format: Digital revista
Language:English
Published: Sociedad Mexicana de Oncología A.C. 2022
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2565-005X2022000500064
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Summary:Abstract Neuroendocrine tumors (NETs) are the most prevalent neoplasm of the small bowel; these present a diagnostic challenge because of their low prevalence and non-specific clinical manifestations. Breast metastasis is rare. We present the case of a 55-year-old female with a painful nodule in the right breast. Mammography reported a solid mass, BBIRADS 4C, with no axillary lymph nodes. Biopsy reported infiltrating ductal carcinoma. Conservative surgery was performed. Histopathology findings are compatible with a well-differentiated (G2) metastatic NET with a gastrointestinal primary. Ga. DOTANOC positron emission tomography/computed tomography scan showed proximal jejunum diffuse mucosal thickening with two foci of increased radiotracer uptake with adjacent adenopathies.