Syphilitic Balanitis of Follmann: Laboratory Pitfalls
ABSTRACT We report a case of early syphilis, presenting as balanitis and papular syphilides in an HIV-infected patient, with a previous history of syphilis infection, which demonstrated a false negative VDRL testing due to a prozone phenomenon. This false negative response results from overwhelming antibody titers, which interfere with the proper formation of the antigen-antibody lattice network, necessary to visualize a positive flocculation test.
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Main Authors: | , , |
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Format: | Digital revista |
Language: | English |
Published: |
Sociedade Portuguesa de Dermatologia e Venereologia
2020
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Online Access: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300062 |
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Summary: | ABSTRACT We report a case of early syphilis, presenting as balanitis and papular syphilides in an HIV-infected patient, with a previous history of syphilis infection, which demonstrated a false negative VDRL testing due to a prozone phenomenon. This false negative response results from overwhelming antibody titers, which interfere with the proper formation of the antigen-antibody lattice network, necessary to visualize a positive flocculation test. |
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