Effect of the Ligand in the Synthesis of 1-Sulfonyl-1,2,3-triazoles Through Copper-Catalyzed Alkyne-Azide Cycloaddition

Copper-catalyzed alkye-azide cycloaddition of p-toluene-sulfonylazide and phenylacetylene was investigated, using catalytic amounts of copper (I) chloride and diverse additives which were tested as copper ligands. The best results were obtained using a catalytic amount of diphenyl disulfide.

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Bibliographic Details
Main Authors: Valencia,Rocío A., Corona,David, Cuevas-Yáñez,Erick
Format: Digital revista
Language:English
Published: Sociedad Química de México A.C. 2012
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1870-249X2012000200012
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Description
Summary:Copper-catalyzed alkye-azide cycloaddition of p-toluene-sulfonylazide and phenylacetylene was investigated, using catalytic amounts of copper (I) chloride and diverse additives which were tested as copper ligands. The best results were obtained using a catalytic amount of diphenyl disulfide.