Effectiveness of diaphragmatic stimulation with single-channel electrodes in rabbits

Every year, a large number of individuals become dependent on mechanical ventilation because of a loss of diaphragm function. The most common causes are cervical spinal trauma and neuromuscular diseases. We have developed an experimental model to evaluate the performance of electrical stimulation of the diaphragm in rabbits using single-channel electrodes implanted directly into the muscle. Various current intensities (10, 16, 20, and 26 mA) produced tidal volumes above the baseline value, showing that this model is effective for the study of diaphragm performance at different levels of electrical stimulation

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Bibliographic Details
Main Authors: Ghedini,Rodrigo Guellner, Espinel,Julio de Oliveira, Felix,Elaine Aparecida, Paludo,Artur de Oliveira, Mariano,Rodrigo, Holand,Arthur Rodrigo Ronconi, Andrade,Cristiano Feijo
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Pneumologia e Tisiologia 2013
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132013000400490
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Summary:Every year, a large number of individuals become dependent on mechanical ventilation because of a loss of diaphragm function. The most common causes are cervical spinal trauma and neuromuscular diseases. We have developed an experimental model to evaluate the performance of electrical stimulation of the diaphragm in rabbits using single-channel electrodes implanted directly into the muscle. Various current intensities (10, 16, 20, and 26 mA) produced tidal volumes above the baseline value, showing that this model is effective for the study of diaphragm performance at different levels of electrical stimulation