Analgesics use for kidney failure

BACKGROUND AND OBJECTIVES:The use of drugs to treat renal failure has particularities due to pharmacokinetic changes present in such population. This study aimed at supplying subsidies for a rational choice of analgesics to be used in patients with renal failure.CONTENTS:Information is provided about pain prevalence and etiology in renal failure patients. In addition, the use of anti-inflammatory drugs, opioid analgesics and adjuvant drugs for pain management is addressed.CONCLUSION:Adjusting pharmacological therapy to renal function impairment may provide effective treatment with less adverse effects.

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Bibliographic Details
Main Authors: Sakata,Rioko Kimiko, Nunes,Marcelo Henrique Gomes
Format: Digital revista
Language:English
Published: Sociedade Brasileira para o Estudo da Dor 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132014000300224
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Summary:BACKGROUND AND OBJECTIVES:The use of drugs to treat renal failure has particularities due to pharmacokinetic changes present in such population. This study aimed at supplying subsidies for a rational choice of analgesics to be used in patients with renal failure.CONTENTS:Information is provided about pain prevalence and etiology in renal failure patients. In addition, the use of anti-inflammatory drugs, opioid analgesics and adjuvant drugs for pain management is addressed.CONCLUSION:Adjusting pharmacological therapy to renal function impairment may provide effective treatment with less adverse effects.