Cutaneous mucinosis in mixed connective tissue disease*

Cutaneous mucinosis is a group of conditions involving an accumulation of mucin or glycosaminoglycan in the skin and its annexes. It is described in some connective tissue diseases but never in association with mixed connective tissue disease. This report concerns two cases of cutaneous mucinosis in patients with mixed connective tissue disease in remission; one patient presented the papular form, and the other reticular erythematous mucinosis. These are the first cases of mucinosis described in mixed connective tissue disease. Both cases had skin lesions with no other clinical or laboratorial manifestations, with clinical response to azathioprine in one, and to an association of chloroquine and prednisone in the other.

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Bibliographic Details
Main Authors: Favarato,Maria Helena Sampaio, Miranda,Sofia Silveira de Castro, Caleiro,Maria Teresa Correia, Assad,Ana Paula Luppino, Halpern,Ilana, Fuller,Ricardo
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2013
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000400635
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Description
Summary:Cutaneous mucinosis is a group of conditions involving an accumulation of mucin or glycosaminoglycan in the skin and its annexes. It is described in some connective tissue diseases but never in association with mixed connective tissue disease. This report concerns two cases of cutaneous mucinosis in patients with mixed connective tissue disease in remission; one patient presented the papular form, and the other reticular erythematous mucinosis. These are the first cases of mucinosis described in mixed connective tissue disease. Both cases had skin lesions with no other clinical or laboratorial manifestations, with clinical response to azathioprine in one, and to an association of chloroquine and prednisone in the other.