A NEW SECO-LIMONOID FROM THE INFLORESCENCES OF Dictyoloma vandellianum
Phytochemical investigation of the inflorescences of Dictyoloma vandellianum A. Juss. (Rutaceae) has led to the isolation of a new A-seco-limonoid, named dictyolomol (1), along with a known quinolone alkaloid, casimiroine (2), previously isolated from the same species. The structures were established by spectroscopic analysis such as one- and two-dimensional NMR, IR, high-resolution mass spectrometry and chemical transformations. The isolated compounds (1 and 2) and O-acetyl derivative (1a) were evaluated for their cytotoxicity against MCF-7 and HeLa cancer cell lines. The results indicated that 1, 1a and 2 showed no significant cytotoxicity.
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Main Authors: | Pereira,Laiane Caline Oliveira, Abreu,Lucas Silva, Silveira,Mayra Bitencourt, Nascimento,Yuri Mangueira do, Souza,Thalisson Amorim de, Hyaric,Mireille Le, Lisboa,Thaís Mangeon Honorato, Sobral,Marianna Vieira, Velozo,Eudes da Silva, Tavares,Josean Fechine, Silva,Marcelo Sobral da |
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Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Química
2020
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422020000500568 |
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