Estudo químico e atividades antiproliferativa, tripanocida e leishmanicida de Maxillaria picta

Estudo químico e atividades antiproliferativa, tripanocida e leishmanicida de Maxillaria picta

The chemical study of the orchid Maxillaria picta resulted in the isolation of the bioactive stilbenes phoyunbene B and phoyunbene C, in addition to four phenolic acids, one xanthone, steroidal compounds and two triterpenes. Crude extract, fractions, subfractions and the isolated xanthone were evaluated for anticancer activity against human tumor cell lines and against evolutionary forms of T. cruzi and L. amazonensis. The structures of the compounds were determined by GC-MS, and ¹H NMR, 13C NMR spectral methods as well as bidimensional techniques.

Saved in:
Bibliographic Details
Main Authors: Almeida,Thiago L. de, Monteiro,Josiane A., Lopes,Greice K. P., Chiavelli,Lucas U. R., Santin,Silvana M. de O., Silva,Cleuza C. da, Kaplum,Vanessa, Scariot,Débora B., Nakamura,Celso V., Ruiz,Ana L. T. G., Carvalho,João E., Faria,Ricardo T. de, Pomini,Armando M.
Format: Digital revista
Language:Portuguese
Published: Sociedade Brasileira de Química 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000700008
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The chemical study of the orchid Maxillaria picta resulted in the isolation of the bioactive stilbenes phoyunbene B and phoyunbene C, in addition to four phenolic acids, one xanthone, steroidal compounds and two triterpenes. Crude extract, fractions, subfractions and the isolated xanthone were evaluated for anticancer activity against human tumor cell lines and against evolutionary forms of T. cruzi and L. amazonensis. The structures of the compounds were determined by GC-MS, and ¹H NMR, 13C NMR spectral methods as well as bidimensional techniques.

Similar Items