Genetic diversity of Echinococcus vogeli in the western Brazilian Amazon

Human polycystic echinococcosis is a parasitic infection caused by the larval stage of Echinococcus vogeli, which occurs in rural areas of Central and South America. Until now, little information on the genetic variability of E. vogeli is available. Here, 32 samples from human-excised E. vogeli cysts had a 396-bp sequence of the mitochondrial cytochrome oxidase I (COI) gene sequenced and compared to another 17 COI sequences representing nine Echinococcus species. A Bayesian COI tree revealed that all E. vogeli sequences formed a monophyletic and well-supported clade with an E. vogeli reference sequence. The occurrence of geographically restricted E. vogeli COI haplotypes suggests retention of ancestral polymorphisms with little migration in Acre, Brazil.

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Bibliographic Details
Main Authors: Daipert-Garcia,Daniel, Pavan,Márcio Galvão, Neves,Leandro Batista das, Almeida,Fernanda Barbosa de, Siqueira,Nilton Ghiotti, Santos,Guilherme Brzoskowski dos, Dias-Correia,Tuan Pedro, Ferreira,Henrique Bunselmeyer, Rodrigues-Silva,Rosângela
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2019
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100417
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Summary:Human polycystic echinococcosis is a parasitic infection caused by the larval stage of Echinococcus vogeli, which occurs in rural areas of Central and South America. Until now, little information on the genetic variability of E. vogeli is available. Here, 32 samples from human-excised E. vogeli cysts had a 396-bp sequence of the mitochondrial cytochrome oxidase I (COI) gene sequenced and compared to another 17 COI sequences representing nine Echinococcus species. A Bayesian COI tree revealed that all E. vogeli sequences formed a monophyletic and well-supported clade with an E. vogeli reference sequence. The occurrence of geographically restricted E. vogeli COI haplotypes suggests retention of ancestral polymorphisms with little migration in Acre, Brazil.