The prevalence of human cytomegalovirus DNA in gliomas of Brazilian patients

Members of the Herpesviridae family have been implicated in a number of tumours in humans. At least 75% of the human population has had contact with cytomegalovirus (HCMV). In this work, we screened 75 Brazilian glioma biopsies for the presence of HCMV DNA sequences. HCMV DNA was detected in 36% (27/75) of the biopsies. It is possible that HCMV could be a co-factor in the evolution of brain tumours.

Saved in:
Bibliographic Details
Main Authors: Fonseca,Renata Fragelli, Kawamura,Marcia Tie, Oliveira,José Antônio, Teixeira,Anselmo, Alves,Gilda, Carvalho,Maria da Glória da Costa
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2012
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000700020
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Members of the Herpesviridae family have been implicated in a number of tumours in humans. At least 75% of the human population has had contact with cytomegalovirus (HCMV). In this work, we screened 75 Brazilian glioma biopsies for the presence of HCMV DNA sequences. HCMV DNA was detected in 36% (27/75) of the biopsies. It is possible that HCMV could be a co-factor in the evolution of brain tumours.