USEFULNESS OF kDNA PCR IN THE DIAGNOSIS OF VISCERAL LEISHMANIASIS REACTIVATION IN CO-INFECTED PATIENTS

SUMMARYIt is important to develop new methods for diagnosing relapses in the co-infection of visceral leishmaniasis (VL) and HIV to enable earlier detection using less invasive methods. We report a case of a co-infected patient who had relapses after VL treatment, where the qualitative kDNA PCR showed a good performance. The kDNA PCR seems to be a useful tool for diagnosing VL and may be a good marker for predicting VL relapses after treatment of co-infected patients with clinical symptoms of the disease.

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Bibliographic Details
Main Authors: Nicodemo,Antonio Carlos, Amato,Valdir Sabbaga, Tuon,Felipe Francisco, Souza,Regina Maia de, Okay,Thelma Suely, Braz,Lúcia Maria Almeida
Format: Digital revista
Language:English
Published: Instituto de Medicina Tropical de São Paulo 2013
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652013000600429
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Summary:SUMMARYIt is important to develop new methods for diagnosing relapses in the co-infection of visceral leishmaniasis (VL) and HIV to enable earlier detection using less invasive methods. We report a case of a co-infected patient who had relapses after VL treatment, where the qualitative kDNA PCR showed a good performance. The kDNA PCR seems to be a useful tool for diagnosing VL and may be a good marker for predicting VL relapses after treatment of co-infected patients with clinical symptoms of the disease.