Recurrencia de Síndrome de Goodpasture con negativización de anticuerpos anti-membrana basal glomerular: Caso clínico

Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset.

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Bibliographic Details
Main Authors: Tagle,Rodrigo, Arancibia,Trinidad, Fischman,Alexandra, Vázquez,Sebastián, Chahuán,Javier, Méndez,Gonzalo P., Huidobro E.,Juan Pablo
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2019
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000300390
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Description
Summary:Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset.