Experiencia de un hospital universitario en el manejo de púrpura trombótico trombocitopénico-microangiopatía trombótica no inmune refractaria o en recaída tratado con rituximab: Report of eight cases

Thrombotic thrombocytopenic purpura, an immune/non-immune thrombotic microangiopathy (TTP/TMA) is associated with high morbidity and mortality, even with appropriate treatment. In patients refractory to standard treatment with plasmapheresis there is no certainty about the best therapeutic strategy. This report shows our experience in eight refractory patients who survived after treatment with rituximab.

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Bibliographic Details
Main Authors: Sarmiento Maldonado,Mauricio, Bertín Cortés-Monroy,Pablo, Lira Vergara,Pablo, Rodríguez Ingles,María Alejandra, García Rodríguez,María José, Ramírez Villanueva,Pablo, Ocqueteau Tachini,Mauricio
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2015
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000600016
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Summary:Thrombotic thrombocytopenic purpura, an immune/non-immune thrombotic microangiopathy (TTP/TMA) is associated with high morbidity and mortality, even with appropriate treatment. In patients refractory to standard treatment with plasmapheresis there is no certainty about the best therapeutic strategy. This report shows our experience in eight refractory patients who survived after treatment with rituximab.