Unusual dissemination patterns of low-grade astrocytomas in childhood

CONTEXT: Low-grade astrocytomas are intracerebral lesions of relatively high frequency in the under-18 pediatric population. They often present indolent behaviour, and complete surgical resection is the choice treatment. In cases where the surgery is not possible, chemotherapy and radiotherapy may be used. Medical reports do not recommend examination of the spinal cord at diagnosis or during treatment, since the risk of dissemination of the lesion to the spine is minimal according to medical experience. We describe here four cases of children with low-grade astrocytoma with aggressive dissemination to the neuroaxis.

Saved in:
Bibliographic Details
Main Authors: Rondinelli,Patricia Imperatriz Porto, Osório,Carlos Alberto Martinez, Cohen,Marcela Pécora, Novaes,Paulo Eduardo Ribeiro Santos
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2008
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000100011
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:CONTEXT: Low-grade astrocytomas are intracerebral lesions of relatively high frequency in the under-18 pediatric population. They often present indolent behaviour, and complete surgical resection is the choice treatment. In cases where the surgery is not possible, chemotherapy and radiotherapy may be used. Medical reports do not recommend examination of the spinal cord at diagnosis or during treatment, since the risk of dissemination of the lesion to the spine is minimal according to medical experience. We describe here four cases of children with low-grade astrocytoma with aggressive dissemination to the neuroaxis.