Exaggerated pulmonary hypertension and right ventricular dysfunction in high-altitude dwellers with patent foramen ovale

There is considerable interindividual variability in pulmonary artery pressure among high-altitude (HA) dwellers, but the underlying mechanism is not known. At low altitude, a patent foramen ovale (PFO) is present in about 25% of the general population. Its prevalence is increased in clinical conditions associated with pulmonary hypertension and arterial hypoxemia, and it is thought to aggravate these problems...

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Bibliographic Details
Main Authors: Brenner, Roman, Pratali, Lorenza, Rimoldi, Stefano F, Murillo Jauregui,Carla Ximena, Soria, Rodrigo, Rexhaj, Emrush, Salinas Salmón, Carlos, Villena, Mercedes, Romero, Catherine, Sartori, Claudio, Allemann, Yves, Scherrer, Urs
Format: Article biblioteca
Language:English
Published: Chest 2015
Subjects:HIPERTENSIÓN PULMONAR, DISFUNCIÓN VENTRICULAR DERECHA,
Online Access:http://repositorio.umsa.bo/xmlui/handle/123456789/7736
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Summary:There is considerable interindividual variability in pulmonary artery pressure among high-altitude (HA) dwellers, but the underlying mechanism is not known. At low altitude, a patent foramen ovale (PFO) is present in about 25% of the general population. Its prevalence is increased in clinical conditions associated with pulmonary hypertension and arterial hypoxemia, and it is thought to aggravate these problems...