Analysis of the Tomato spotted wilt virus ambisense S RNA-encoded hairpin structure in translation
The intergenic region (IR) of ambisense RNA segments from animal- and plant-infecting (-)RNA viruses functions as a bidirectional transcription terminator. The IR sequence of the Tomato spotted wilt virus (TSWV) ambisense S RNA contains stretches that are highly rich in A-residues and U-residues and is predicted to fold into a stable hairpin structure. The presence of this hairpin structure sequence in the 3' untranslated region (UTR) of TSWV mRNAs implies a possible role in translation.
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| Main Authors: | , , , , |
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| Format: | Article/Letter to editor biblioteca |
| Language: | English |
| Subjects: | affecting transcription termination, cap-snatching mechanism, cdna-based rescue, escherichia-coli rna, influenza-virus, intergenic region, messenger-rna, nonstructural protein nss, stem-loop structure, tail-independent translation, |
| Online Access: | https://research.wur.nl/en/publications/analysis-of-the-tomato-spotted-wilt-virus-ambisense-s-rna-encoded |
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| Summary: | The intergenic region (IR) of ambisense RNA segments from animal- and plant-infecting (-)RNA viruses functions as a bidirectional transcription terminator. The IR sequence of the Tomato spotted wilt virus (TSWV) ambisense S RNA contains stretches that are highly rich in A-residues and U-residues and is predicted to fold into a stable hairpin structure. The presence of this hairpin structure sequence in the 3' untranslated region (UTR) of TSWV mRNAs implies a possible role in translation. |
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