Multi-block copolymers

A multi-block copolymer comprises at least one hydrophilic collagen-like block and at least one silk-like block. The silk-like block comprises an amino acid sequence ((GA) m GX) n , wherein G is glycine, A is alanine, m and n are at least 2. X is an ionizable amino acid. The ionizable amino acid is inducible to bear a positive charge or a negative charge. The ionizable amino acid bearing the positive charge is preferably histidine and the one bearing the negative charge is preferably glutamic acid.

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Bibliographic Details
Main Authors: de Wolf, F.A., Cohen Stuart, M.A., Eggink, G., Werten, M.W.T., Martens, A.A.
Format: Patent biblioteca
Language:English
Subjects:Life Science,
Online Access:https://research.wur.nl/en/publications/multi-block-copolymers
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Description
Summary:A multi-block copolymer comprises at least one hydrophilic collagen-like block and at least one silk-like block. The silk-like block comprises an amino acid sequence ((GA) m GX) n , wherein G is glycine, A is alanine, m and n are at least 2. X is an ionizable amino acid. The ionizable amino acid is inducible to bear a positive charge or a negative charge. The ionizable amino acid bearing the positive charge is preferably histidine and the one bearing the negative charge is preferably glutamic acid.