Exploration of aggregate exposure to compounds present in food

This report describes the result of a study into the exposure to harmful compounds via more than one source / route (so-called aggregate exposure) in relation to the relevance of extending dietary exposure assessments as performed using the Monte Carlo Risk Assessment (MCRA) programme with other sources than diet (and drinking water) or other routes. An overview is given of relevant groups of compounds for which aggregate exposure may be relevant, and of models available to calculate aggregate exposure, including NORMTOX and several American models. Also relevant stakeholders of aggregate exposure are identified.

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Bibliographic Details
Main Authors: Boon, P.E., Ragas, A.M.J., van Klaveren, J.D.
Format: External research report biblioteca
Language:English
Published: RIKILT
Subjects:diet, drinking water, exposure, exposure assessment, mathematical models, modeling, monte carlo method, toxic substances, blootstelling, blootstellingsbepaling, dieet, drinkwater, modelleren, monte carlo-methode, toxische stoffen, wiskundige modellen,
Online Access:https://research.wur.nl/en/publications/exploration-of-aggregate-exposure-to-compounds-present-in-food
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Summary:This report describes the result of a study into the exposure to harmful compounds via more than one source / route (so-called aggregate exposure) in relation to the relevance of extending dietary exposure assessments as performed using the Monte Carlo Risk Assessment (MCRA) programme with other sources than diet (and drinking water) or other routes. An overview is given of relevant groups of compounds for which aggregate exposure may be relevant, and of models available to calculate aggregate exposure, including NORMTOX and several American models. Also relevant stakeholders of aggregate exposure are identified.