Risk factors for clinical signs of PMWS and PDNS in pigs in the Netherlands: a case-control study = Bedrijfsrisicofactoren voor varkens met klinische verschijnselen van PMWS of PDNS in Nederland : een case-control onderzoek the Netherlands: a case-control study
Potential risk factors for clinical signs of post-weaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS) in pigs in the Netherlands were investigated in a matched case-control study using a questionnaire (personal interview). Eighty-two pig farmers were questioned about management, hygiene, husbandry systems, disease history, and preventive health care. In this study, 30 pig herds with (cases) and 30 pig herds without (controls) characteristic clinical signs of PMWS were compared. For PDNS, 11 pig herds with (cases) and 11 pig herds without (controls) characteristic clinical signs of PDNS were compared. Univariate analysis (P <0.10) showed that the following occurred relatively more often in the PMWS case herds than in the control herds: 1) clinical signs of PDNS, porcine reproductive and respiratory syndrome (PRRS), porcine parvovirus (PPV) infections, meningitis, coccidiosis, and pre-weaning diarrhoea observed by the farmer; 2) vaccination against PRRS and mycoplasma; 3) non-optimal climatic conditions in the nursery rooms, a large variation in weaning age, a high occurrence of cross-fostering of piglets, a large number of sows with lactation problems, poor colostrum intake by piglets; and 4) historical) use of breeding stock (including semen for artifi cial insemination) of Anglo-Saxon origin. In the fi nal multivariate statistical model, one variable remained signifi cantly associated with PMWS case herds, namely, the presence of clinical signs of PRRS (and/or the associated use of vaccination against PRRS). It should be noted that in almost all cases animals were vaccinated against PRRS because of clinical signs of PRRS that appeared a few months after the first occurrence of clinical signs of PMWS. This excludes PRRS vaccination as a primary factor in causing PMWS. Analysis of the PDNS case-control data showed comparable results with those of the PMWS study. In the fi nal statistical model, the presence of clinical signs of PRRS (and/or the associated use of vaccination against PRRS) was signifi cantly associated with PDNS case herds.
| Main Authors: | , , |
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| Format: | Article/Letter to editor biblioteca |
| Language: | English |
| Subjects: | animal disease prevention, conventional pigs, dermatitis, experimental inoculation, experimental reproduction, farm management, multisystemic wasting syndrome, nephropathy syndrome, pasteurella-multocida, porcine circovirus type-2, porcine circoviruses, porcine reproductive and respiratory syndrome, respiratory syndrome virus, risk factors, swine diseases, syndrome pmws, agrarische bedrijfsvoering, dierziektepreventie, risicofactoren, varkenscircovirussen, varkensziekten, voortplantings- en ademhalingssyndroom bij varkens, |
| Online Access: | https://research.wur.nl/en/publications/risk-factors-for-clinical-signs-of-pmws-and-pdns-in-pigs-in-the-n |
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| Summary: | Potential risk factors for clinical signs of post-weaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS) in pigs in the Netherlands were investigated in a matched case-control study using a questionnaire (personal interview). Eighty-two pig farmers were questioned about management, hygiene, husbandry systems, disease history, and preventive health care. In this study, 30 pig herds with (cases) and 30 pig herds without (controls) characteristic clinical signs of PMWS were compared. For PDNS, 11 pig herds with (cases) and 11 pig herds without (controls) characteristic clinical signs of PDNS were compared. Univariate analysis (P <0.10) showed that the following occurred relatively more often in the PMWS case herds than in the control herds: 1) clinical signs of PDNS, porcine reproductive and respiratory syndrome (PRRS), porcine parvovirus (PPV) infections, meningitis, coccidiosis, and pre-weaning diarrhoea observed by the farmer; 2) vaccination against PRRS and mycoplasma; 3) non-optimal climatic conditions in the nursery rooms, a large variation in weaning age, a high occurrence of cross-fostering of piglets, a large number of sows with lactation problems, poor colostrum intake by piglets; and 4) historical) use of breeding stock (including semen for artifi cial insemination) of Anglo-Saxon origin. In the fi nal multivariate statistical model, one variable remained signifi cantly associated with PMWS case herds, namely, the presence of clinical signs of PRRS (and/or the associated use of vaccination against PRRS). It should be noted that in almost all cases animals were vaccinated against PRRS because of clinical signs of PRRS that appeared a few months after the first occurrence of clinical signs of PMWS. This excludes PRRS vaccination as a primary factor in causing PMWS. Analysis of the PDNS case-control data showed comparable results with those of the PMWS study. In the fi nal statistical model, the presence of clinical signs of PRRS (and/or the associated use of vaccination against PRRS) was signifi cantly associated with PDNS case herds. |
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