Microbiological preparation of a atisenolides by Gibberella fujikuroi

The microbiological transformation of ent-19-hydrosyatis-6.16-diene into 3a,7B-dihydroxyatisenolide and 7B,18-dihydroxyatisenolide, and of ent-atis-6,16-dien-19-oic acid into 7B-hydroxyatisenolide, 3a,7B-dihydroxyatisenolide and 7B,18-dihydroxyatisenolide, using the fungus Gibberella fujikuroi have been carried out. The substrates have been prepared from gummiferolic acid.

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Bibliographic Details
Main Authors: Fraga, Braulio M., Guillermo, Ricardo, Hanson, James R.
Other Authors: Comisión Interministerial de Ciencia y Tecnología, CICYT (España)
Format: artículo biblioteca
Language:English
Published: Elsevier 1992
Subjects:Gibberella fujikuroi, Diterpenes, Kaurenolides, Atisenolides, Gummiferolic acid,
Online Access:http://hdl.handle.net/10261/21879
http://dx.doi.org/10.13039/501100007273
http://dx.doi.org/10.13039/501100003339
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Summary:The microbiological transformation of ent-19-hydrosyatis-6.16-diene into 3a,7B-dihydroxyatisenolide and 7B,18-dihydroxyatisenolide, and of ent-atis-6,16-dien-19-oic acid into 7B-hydroxyatisenolide, 3a,7B-dihydroxyatisenolide and 7B,18-dihydroxyatisenolide, using the fungus Gibberella fujikuroi have been carried out. The substrates have been prepared from gummiferolic acid.