Oximoaspergillimide, a fungal derivative from a marine isolate of Aspergillus sp
A new alkaloid, oximoaspergillimide (1), and the known neohydroxyaspergillic (2) and neoaspergillic (3) acids, have been isolated from the extract of a cultured marine‐derived fungus (strain CF07002) identified as a member of the genus Aspergillus. The structure of 1 was determined by interpretation of NMR spectroscopic data, and confirmed by synthesis. The antimicrobial and cytotoxic activities of compounds 1–3 were evaluated.
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| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Published: |
Wiley-VCH
2015-04
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| Subjects: | Alkaloids: Oximes, Cytotoxicity, Antimicrobial activity, Natural products, Structure elucidation, |
| Online Access: | http://hdl.handle.net/10261/181213 http://dx.doi.org/10.13039/501100003725 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100011017 |
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| Summary: | A new alkaloid, oximoaspergillimide (1), and the known neohydroxyaspergillic (2) and neoaspergillic (3) acids, have been isolated from the extract of a cultured marine‐derived fungus (strain CF07002) identified as a member of the genus Aspergillus. The structure of 1 was determined by interpretation of NMR spectroscopic data, and confirmed by synthesis. The antimicrobial and cytotoxic activities of compounds 1–3 were evaluated. |
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