Efficient synthesis of benzocyclotrimer analogues by Negishi cross-coupling and intramolecular nucleophilic substitution
We report a new and efficient synthetic strategy that allows access to flexible and functionalized benzocyclotrimers under mild conditions and in few steps. The Negishi cross-coupling reaction was used for the C-C bond formation, whereas intramolecular O-alkylations provided the oxepane rings.
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| Main Authors: | , |
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| Format: | artículo biblioteca |
| Published: |
Royal Society of Chemistry (UK)
2017-12-04
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| Subjects: | synthesis, Negishi cross-coupling, Benzocyclotrimer, |
| Online Access: | http://hdl.handle.net/10261/179517 |
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| Summary: | We report a new and efficient synthetic strategy that allows access to flexible and functionalized benzocyclotrimers under mild conditions and in few steps. The Negishi cross-coupling reaction was used for the C-C bond formation, whereas intramolecular O-alkylations provided the oxepane rings. |
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