Workshop studies with monoclonal antibodies identifying a novel porcine differentiation antigen, SWC9

Two monoclonal antibodies (mAb) within cluster M4 of the myeloid section of the Second International Swine CD Workshop, C4 (No. 144) and PM18-7 (No. 192), showed reactivity with thymocytes and among cells of myelomonocytic origin with mature macrophages but not with monocytes and granulocytes. Both mAb recognize a protein showing two bands of 205 kDa and 130 kDa under both reducing and non-reducing conditions. Although epitope mapping with these mAb could not be performed, this cluster received the SWC9 designation.

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Bibliographic Details
Main Authors: Dominguez, J., Ezquerra, A., Alonso, F., Bullido, R., McCullough, K., Summerfield, A., Bianchi, A., Zwart, R. J., Kim, Y. B., Blecha, F., Eicher, S., Murtaugh, M. P., Pampusch, M., Burger, K.
Format: conference object biblioteca
Language:eng
Published: 1998
Online Access:http://hdl.handle.net/20.500.12792/1120
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Description
Summary:Two monoclonal antibodies (mAb) within cluster M4 of the myeloid section of the Second International Swine CD Workshop, C4 (No. 144) and PM18-7 (No. 192), showed reactivity with thymocytes and among cells of myelomonocytic origin with mature macrophages but not with monocytes and granulocytes. Both mAb recognize a protein showing two bands of 205 kDa and 130 kDa under both reducing and non-reducing conditions. Although epitope mapping with these mAb could not be performed, this cluster received the SWC9 designation.