MEK signalling pathway is required for hypoblast specification and migration in ovine

MEK signalling pathway is required for hypoblast specification and migration in ovine

MEK signalling pathway is required for hypoblast differentiation in mouse embryos, but its role in ungulate embryos remains controversial. This paper demonstrates that MEK is required for hypoblast specification in the inner cell mass of the ovine blastocyst and that it plays a role during the hypoblast migration occurring following blastocyst hatching.

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Bibliographic Details
Main Authors: Martínez de Los Reyes, Nuria, Flores-Borobia, Inés, Carvajal-Serna, Melissa, Marigorta, Pilar, Bermejo Álvarez, Pablo, Ramos Ibeas, Priscila
Other Authors: Martínez de Los Reyes, Nuria [0009-0009-1578-5537]
Format: artículo biblioteca
Language:English
Published: BioScientífica 2024-04-29
Online Access:http://hdl.handle.net/10261/358267
https://api.elsevier.com/content/abstract/scopus_id/85191700511
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Summary:MEK signalling pathway is required for hypoblast differentiation in mouse embryos, but its role in ungulate embryos remains controversial. This paper demonstrates that MEK is required for hypoblast specification in the inner cell mass of the ovine blastocyst and that it plays a role during the hypoblast migration occurring following blastocyst hatching.

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