The Iberian pig fed with high-fat diet: a model of renal disease in obesity and metabolic syndrome

The pathogenesis of renal disease in the context of overweight/obesity, metabolic syndrome, and insulin resistance is not completely understood. This may be due to the lack of a definitive animal model of disease, which limits our understanding of obesity-induced renal damage. We evaluated the changes in renal histology and lipid deposits induced by obesity in a model of insulin resistance: the Iberian swine fed with fat-enriched food.

Saved in:
Bibliographic Details
Main Authors: Rodríguez, Rosario Miquel, González De Bulnes, Antonio, Garcia-Contreras, Consolacion, Rodríguez-Rodríguez, Ana Elena, Astiz, Susana, Vázquez-Gómez, M., Pesántez-Pacheco, José Luis, Isabel, Beatriz, Salido-Ruiz, Eduardo, González, Jorge M., Donate Correa, Javier, Luis-Lima, Sergio, Porrini, Esteban
Other Authors: Instituto de Salud Carlos III
Format: artículo biblioteca
Language:English
Published: Springer Nature 2020-02-01
Online Access:http://hdl.handle.net/10261/343865
http://dx.doi.org/10.13039/501100004587
http://dx.doi.org/10.13039/501100000780
https://api.elsevier.com/content/abstract/scopus_id/85074602485
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The pathogenesis of renal disease in the context of overweight/obesity, metabolic syndrome, and insulin resistance is not completely understood. This may be due to the lack of a definitive animal model of disease, which limits our understanding of obesity-induced renal damage. We evaluated the changes in renal histology and lipid deposits induced by obesity in a model of insulin resistance: the Iberian swine fed with fat-enriched food.