Workshop studies on monoclonal antibodies in the myeloid panel with CD11 specificity
Several putative anti-human and swine CD11-specific monoclonal antibodies (mAbs) were included in the myeloid section of the Third International Swine CD Workshop. Failure of clustering analysis to group these mAbs together prompted additional analyses to define the specificities of these mAb. Combination of one and two-color flow cytometry (FCM) and immunoprecipitation (IP) allowed the definition of the mAb into three CD11 groups. Cellular distribution of the molecules recognized by anti-human CD11b and c mAbs on swine cells proved to be significantly different from that found in humans. Copyright © 2001 .
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| Main Authors: | , , , , , , , |
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| Format: | artículo biblioteca |
| Language: | English |
| Published: |
Elsevier
2001
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| Subjects: | Pig, Cluster of differentiation (CD) antigens, Monoclonal antibodies (mAb), Myeloid cells, CD11b, CD11R, |
| Online Access: | http://hdl.handle.net/20.500.12792/1117 http://hdl.handle.net/10261/292192 |
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| Summary: | Several putative anti-human and swine CD11-specific monoclonal antibodies (mAbs) were included in the myeloid section of the Third International Swine CD Workshop. Failure of clustering analysis to group these mAbs together prompted additional analyses to define the specificities of these mAb. Combination of one and two-color flow cytometry (FCM) and immunoprecipitation (IP) allowed the definition of the mAb into three CD11 groups. Cellular distribution of the molecules recognized by anti-human CD11b and c mAbs on swine cells proved to be significantly different from that found in humans. Copyright © 2001 . |
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