Neurodegenerative diseases

Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease are major causes of death worldwide and are characterized by a progressive loss of specific neuronal cells. Although the discovery of new drugs for these neurodegenerative diseases is still challenging, in recent years, natural phlorotannins and bromophenols contained in marine sources have shown protective activities from different neurodegenerative disorders and, therefore, might be good candidates for the development of new drugs. Data shown in this chapter indicate a sustained body of evidence on the ability of edible seaweeds to modulate multi-mechanisms involved in the prevention of neurodegenerative diseases. However, some aspects to be further explored during the following years emerge from this review, apart from confirming the results derived from in vitro and in vivo studies, particularly human studies.

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Bibliographic Details
Main Author: Mateos, Raquel
Format: capítulo de libro biblioteca
Language:English
Published: Elsevier 2023
Online Access:http://hdl.handle.net/10261/354289
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Summary:Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease are major causes of death worldwide and are characterized by a progressive loss of specific neuronal cells. Although the discovery of new drugs for these neurodegenerative diseases is still challenging, in recent years, natural phlorotannins and bromophenols contained in marine sources have shown protective activities from different neurodegenerative disorders and, therefore, might be good candidates for the development of new drugs. Data shown in this chapter indicate a sustained body of evidence on the ability of edible seaweeds to modulate multi-mechanisms involved in the prevention of neurodegenerative diseases. However, some aspects to be further explored during the following years emerge from this review, apart from confirming the results derived from in vitro and in vivo studies, particularly human studies.