Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio

Sixteen compounds incluiding four benzofurans (1–4), three benzoic acid derivatives (6–8), one eremophilane (9), four diterpenes (10–13) and four pyrrolizidine alkaloids (14–17) were isolated from Senecio subcandidus, S. klugii and S. ayapatensis from Perú. Compounds 1–4 and 6–9 have not been previously reported as natural products. Their molecular structures were determined by NMR spectroscopic analysis, comparison with published NMR data and chemical transformations. The X-ray analysis of acetylated derivative 5 and compound 7 were also performed. Their insecticidal and antifungal activities were tested.

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Bibliographic Details
Main Authors: Ruiz-Vasquez, Liliana, Ruiz-Mesía, Lastenia, Reina, Matías, López-Rodríguez, Matías, González-Platas, Javier, Giménez, Cristina, Cabrera, Raimundo, González-Coloma, Azucena
Other Authors: Ministerio de Economía, Industria y Competitividad (España)
Format: artículo biblioteca
Published: Elsevier 2018-12
Subjects:Senecio, Benzofurans, Benzoic acid derivatives, Diterpenes, Pyrrolizidine alkaloids, Asteraceae,
Online Access:http://hdl.handle.net/10261/179474
http://dx.doi.org/10.13039/501100010198
http://dx.doi.org/10.13039/501100003339
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Summary:Sixteen compounds incluiding four benzofurans (1–4), three benzoic acid derivatives (6–8), one eremophilane (9), four diterpenes (10–13) and four pyrrolizidine alkaloids (14–17) were isolated from Senecio subcandidus, S. klugii and S. ayapatensis from Perú. Compounds 1–4 and 6–9 have not been previously reported as natural products. Their molecular structures were determined by NMR spectroscopic analysis, comparison with published NMR data and chemical transformations. The X-ray analysis of acetylated derivative 5 and compound 7 were also performed. Their insecticidal and antifungal activities were tested.