Insights into mammalian TE diversity through the curation of 248 genome assemblies

[INTRODUCTION] An estimated 160 million years have passed since the first placental mammals evolved. These eutherians are categorized into 19 orders consisting of nearly 4000 extant species, with ~70% being bats or rodents. Broad, in-depth, and comparative genomic studies across Eutheria have previously been unachievable because of the lack of genomic resources. The collaboration of the Zoonomia Consortium made available hundreds of high-quality genome assemblies for comparative analysis. Our focus within the consortium was to investigate the evolution of transposable elements (TEs) among placental mammals. Using these data, we identified previously known TEs, described previously unknown TEs, and analyzed the TE distribution among multiple taxonomic levels.

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Bibliographic Details
Main Authors: Osmanski, Austin B., Paulat, Nicole S., Korstian, Jenny, Grimshaw, Jenna R., Halsey, Michaela, Sullivan, Kevin A. M., Moreno-Santillán, Diana D., Crookshanks, Claudia, Roberts, Jacquelyn, Garcia, Carlos, Johnson, Matthew G., Densmore, Llewellyn D., Stevens, Richard D., Zoonomia Consortium, Juan, David, Marqués-Bonet, Tomàs, Muntané, Gerard, Navarro, Arcadi, Serres-Armero, Aitor, Valenzuela, Alejandro, Rosen, Jeb, Storer, Jessica M., Hubley, Robert, Smit, Arian F. A., Dávalos, Liliana M., Karlsson, Elinor K., Lindblad-Toh, Kerstin, Ray, David A.
Other Authors: National Science Foundation (US)
Format: artículo biblioteca
Language:English
Published: American Association for the Advancement of Science 2023-04-28
Online Access:http://hdl.handle.net/10261/348268
http://dx.doi.org/10.13039/100000001
http://dx.doi.org/10.13039/100000002
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Summary:[INTRODUCTION] An estimated 160 million years have passed since the first placental mammals evolved. These eutherians are categorized into 19 orders consisting of nearly 4000 extant species, with ~70% being bats or rodents. Broad, in-depth, and comparative genomic studies across Eutheria have previously been unachievable because of the lack of genomic resources. The collaboration of the Zoonomia Consortium made available hundreds of high-quality genome assemblies for comparative analysis. Our focus within the consortium was to investigate the evolution of transposable elements (TEs) among placental mammals. Using these data, we identified previously known TEs, described previously unknown TEs, and analyzed the TE distribution among multiple taxonomic levels.