​Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs

[INTRODUCTION] It has been almost 100 years since the sled dog Balto helped save the community of Nome, Alaska, from a diphtheria outbreak. Today, Balto symbolizes the indomitable spirit of the sled dog. He is immortalized in statue and film, and is physically preserved and on display at the Cleveland Museum of Natural History. Balto represents a dog population that was reputed to tolerate harsh conditions at a time when northern communities were reliant on sled dogs. Investigating Balto’s genome sequence using technologies for sequencing degraded DNA offers a new perspective on this historic population.

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Bibliographic Details
Main Authors: Moon, Katherine L., Huson, Heather J., Morrill, Kathleen, Wang, Ming-Shan, Li, Xue, Srikanth, Krishnamoorthy, Zoonomia Consortium, Juan, David, Marqués-Bonet, Tomàs, Muntané, Gerard, Navarro, Arcadi, Serres-Armero, Aitor, Valenzuela, Alejandro, Lindblad-Toh, Kerstin, Svenson, Gavin J., Karlsson, Elinor K., Shapiro, Beth
Other Authors: National Institutes of Health (US)
Format: artículo biblioteca
Language:English
Published: American Association for the Advancement of Science 2023-04-28
Online Access:http://hdl.handle.net/10261/347939
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Summary:[INTRODUCTION] It has been almost 100 years since the sled dog Balto helped save the community of Nome, Alaska, from a diphtheria outbreak. Today, Balto symbolizes the indomitable spirit of the sled dog. He is immortalized in statue and film, and is physically preserved and on display at the Cleveland Museum of Natural History. Balto represents a dog population that was reputed to tolerate harsh conditions at a time when northern communities were reliant on sled dogs. Investigating Balto’s genome sequence using technologies for sequencing degraded DNA offers a new perspective on this historic population.