rs12416605:C>T in MIR938 associates with gastric cancer through affecting the regulation of the CXCL12 chemokine gene
[Background] MicroRNAs are small regulatory RNAs with important roles in carcinogenesis. Genetic variants in these regulatory molecules may contribute to disease. We aim to identify allelic variants in microRNAs as susceptibility factors to gastric cancer using association studies and functional approaches.
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Main Authors: | , , , , , , , , |
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Other Authors: | |
Format: | artículo biblioteca |
Published: |
John Wiley & Sons
2019-08
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Subjects: | functional SNV, Gastric cancer, gene regulation, Genetic susceptibility, microRNA, |
Online Access: | http://hdl.handle.net/10261/207034 http://dx.doi.org/10.13039/501100002850 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100004587 |
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Summary: | [Background] MicroRNAs are small regulatory RNAs with important roles in carcinogenesis. Genetic variants in these regulatory molecules may contribute to disease. We aim to identify allelic variants in microRNAs as susceptibility factors to gastric cancer using association studies and functional approaches. |
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