Revealing microbial recognition by specific antibodies
[Background] Recognition of microorganisms by antibodies is a vital component of the human immune response. However, there is currently very limited understanding of immune recognition of 50 % of the human microbiome which is made up of as yet un-culturable bacteria. We have combined the use of flow cytometry and pyrosequencing to describe the microbial composition of human samples, and its interaction with the immune system.
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| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Published: |
BioMed Central
2015-07-02
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| Subjects: | Immunoglobulin, Flow cytometry, Pyrosequencing, 16S rRNA, Opsonization, Human microbiome, |
| Online Access: | http://hdl.handle.net/10261/125850 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100004587 http://dx.doi.org/10.13039/501100003359 |
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| Summary: | [Background]
Recognition of microorganisms by antibodies is a vital component of the human immune response. However, there is currently very limited understanding of immune recognition of 50 % of the human microbiome which is made up of as yet un-culturable bacteria. We have combined the use of flow cytometry and pyrosequencing to describe the microbial composition of human samples, and its interaction with the immune system. |
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