Salmonella enterica serotype typhi with nonclassical quinolone resistance phenotype
We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.
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| Main Authors: | , , , , , , |
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| Format: | article biblioteca |
| Language: | eng |
| Subjects: | S50 - Santé humaine, Salmonella, sérotype, Résistance aux antibiotiques, antibiotique, typhoïde, http://aims.fao.org/aos/agrovoc/c_6757, http://aims.fao.org/aos/agrovoc/c_32699, http://aims.fao.org/aos/agrovoc/c_8848, http://aims.fao.org/aos/agrovoc/c_492, http://aims.fao.org/aos/agrovoc/c_29244, http://aims.fao.org/aos/agrovoc/c_3081, http://aims.fao.org/aos/agrovoc/c_8068, http://aims.fao.org/aos/agrovoc/c_666, |
| Online Access: | http://agritrop.cirad.fr/567157/ http://agritrop.cirad.fr/567157/1/document_567157.pdf |
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| Summary: | We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure. |
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