Candidate genes for production traits in Nelore beef cattle.

Candidate genes for production traits in Nelore beef cattle.

Meat quality is an important trait for the beef industry. Backfat thickness, ribeye area, and shear force are traits measured late in life, and the investigation of molecular markers associated with these traits can help breeding programs. In cattle, some polymorphisms have been related to production traits. Thus, the purpose of this study was to assess the presence of polymorphisms in the candidate genes insulin-like growth factor 1 (IGF1), fatty acid-binding protein 4 (FABP4), and peroxisome proliferative active receptor gamma coactivator 1 A (PPARGC1A) and associate them with production traits in reference families of Nelore cattle. We used 270 steers descendent from 20 sires that were chosen to represent variability in this breed. The investigation of marker effects on the traits was performed using a mixed model under the restricted maximum likelihood method. A significant allele substitution effect was found for IGF1 and yearling weight (P ? 0.017). The mean allele substitution effect was 6.9 kg, with the 229 allele associated with reduced yearling weight in this Nelore population.

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Bibliographic Details
Main Authors: TIZIOTO, P. C., MEIRELLES, S. L., TULLIO, R. R., ROSA, A. do N., ALENCAR, M. M. de, MEDEIROS, S. R. de, SIQUEIRA, F., FEIJO, G. L. D., SILVA, L. O. C. da, TORRES JUNIOR, R. A. de A., REGITANO, L. C. de A.
Other Authors: P. C. TIZIOTO, Universidade Federal de São Carlos; SARAH L. MEIRELLES, Universidade Federal de Lavras; RYMER RAMIZ TULLIO, CPPSE; ANTONIO DO NASCIMENTO ROSA, CNPGC; MAURICIO MELLO DE ALENCAR, CPPSE; SERGIO RAPOSO DE MEDEIROS, CNPGC; FABIANE SIQUEIRA, CNPGC; GELSON LUIS DIAS FEIJO, CNPGC; LUIZ OTAVIO CAMPOS DA SILVA, CNPGC; ROBERTO AUGUSTO DE A TORRES JUNIOR, CNPGC; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Format: Artigo de periódico biblioteca
Language:Ingles
English
Published: 2013-01-07
Subjects:Polymorphisms, Insulin like growth factor, Yearling weight, Bos Indicus,
Online Access:http://www.alice.cnptia.embrapa.br/alice/handle/doc/944232
http://dx.doi.org/10.4238/2012
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Summary:Meat quality is an important trait for the beef industry. Backfat thickness, ribeye area, and shear force are traits measured late in life, and the investigation of molecular markers associated with these traits can help breeding programs. In cattle, some polymorphisms have been related to production traits. Thus, the purpose of this study was to assess the presence of polymorphisms in the candidate genes insulin-like growth factor 1 (IGF1), fatty acid-binding protein 4 (FABP4), and peroxisome proliferative active receptor gamma coactivator 1 A (PPARGC1A) and associate them with production traits in reference families of Nelore cattle. We used 270 steers descendent from 20 sires that were chosen to represent variability in this breed. The investigation of marker effects on the traits was performed using a mixed model under the restricted maximum likelihood method. A significant allele substitution effect was found for IGF1 and yearling weight (P ? 0.017). The mean allele substitution effect was 6.9 kg, with the 229 allele associated with reduced yearling weight in this Nelore population.

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