Detection of quantitative trait loci for growth traits on bovine chromosome 2.

Classical quantitative genetic approach is applied successfully to improve livestock production using phenotype and pedigree information to estimate population genetic parameters such as heritabilities, genetics variances and genetic correlations. However, this process is slow and there is no knowledge of the genetic architecture of the quantitative traits. Molecular genetics techniques can be used to identify genes or chromosomal regions (Quantitative Trait Loci - QTL) that affect traits of importance in livestock production. Genetic response can be improved by direct selection on genes or genomic regions that affect economic traits through marker-assisted selection (MAS) or gene introgression (Dekkers and Hospital, 2002). The objective of this study was to detect QTL affecting growth traits in BTA 2 using F2 Holstein x Gyr population and microsatellite markers.

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Bibliographic Details
Main Authors: MOURÃO, G. B., SALEM, M. M. I, PACKER, U. I., PINTO, L. F. B., MACHADO, M. A., GASPARIN, G., AZEVEDO, A. L. S., VERNEQUE, R. da S., REGITANO, L. C. de A.
Other Authors: G. B. MOURÃO, ESALQ-USP/PIRACICABA; M. M. I. SALEM, ESALQ-USP/PIRACICABA; UMBERTO IRENEU PACKER, ESALQ-USP/PIRACICABA; L. F. B. PINTO, ESALQ-USP/PIRACIBA; MARCO ANTONIO MACHADO, CNPGL; GUSTAVO GASPARIN, ESALQ-USP/PIRACICABA; ANA LUISA SOUSA AZEVEDO, CNPGL; RUI DA SILVA VERNEQUE, CNPGL; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Format: Artigo em anais e proceedings biblioteca
Language:eng
Published: 2011-01-04
Subjects:Chromosome, Bovine, QTL, Microsatellite markers,
Online Access:http://www.alice.cnptia.embrapa.br/alice/handle/doc/871589
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Summary:Classical quantitative genetic approach is applied successfully to improve livestock production using phenotype and pedigree information to estimate population genetic parameters such as heritabilities, genetics variances and genetic correlations. However, this process is slow and there is no knowledge of the genetic architecture of the quantitative traits. Molecular genetics techniques can be used to identify genes or chromosomal regions (Quantitative Trait Loci - QTL) that affect traits of importance in livestock production. Genetic response can be improved by direct selection on genes or genomic regions that affect economic traits through marker-assisted selection (MAS) or gene introgression (Dekkers and Hospital, 2002). The objective of this study was to detect QTL affecting growth traits in BTA 2 using F2 Holstein x Gyr population and microsatellite markers.