Candidate genes for production traits in reference families of Nellore beef cattle.

Candidate genes for production traits in reference families of Nellore beef cattle.

Brazil has the second largest herd of cattle in the world (Anualpec (2008)) with predominance of Bos indicus breeds which have a higher heat tolerance, resistance to parasites and fertility than cattle of European origin. Interest in improving carcass and beef quality is growing in the National beef industry, pressured by the requirements of meat markets. The quantification of genetic variation and exploration of genomic segments that influence carcass and beef quality in the breeding population are essential for the establishment of quantitative and molecular criteria for selection. The PPARGC1A (peroxisome proliferative active receptor gamma coactivator 1 A), FABP4 (fatty acid binding protein 4) and IGF-1 (insulin-like growth factor) genes are candidates to influence production traits in cattle. Association of polymorphisms in these genes with production traits were reported but studies with the populations where marker assisted selection is to be applied are still necessary before this information can effectively be used by producers. The aim of this study was to investigate the presence of polymorphisms in the candidate genes PPARGC1A, FABP4 and IGF-1in reference families of Nellore cattle and relate them to meat production traits in these animals.

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Bibliographic Details
Main Authors: TIZIOTO, P. C., VENERONI, G. B., MEIRELLES, S. L., SIQUEIRA, F., ROSA, A. do N., SILVA, L. O. C. da, MEDEIROS, S. R. de, TORRES JUNIOR, R. A. de A., TULLIO, R. R., ALENCAR, M. M. de, NASCIMENTO, M. L., SOUZA, A. R. D. L., FEIJO, G. L. D., REGITANO, L. C. de A.
Other Authors: UFSCar DE SÃO CARLOS, SP.; UFSCar DE SÃO CARLOS, SP.; SARAH L. MEIRELLES, POS-GRADUANDA DA UNESP DE JABOTICABAL,SP.; FABIANE SIQUEIRA, CNPGC; ANTONIO DO NASCIMENTO ROSA, CNPGC; LUIZ OTAVIO CAMPOS DA SILVA, CNPGC; SERGIO RAPOSO DE MEDEIROS, CNPGC; ROBERTO AUGUSTO DE A TORRES JUNIOR, CNPGC; RYMER RAMIZ TULLIO, CPPSE; MAURICIO MELLO DE ALENCAR, CPPSE; ESALQ-USP DE PIRACICABA,SP.; ESALQ-USP DE PIRACICABA,SP.; GELSON LUIS DIAS FEIJO, CNPGC; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Format: Separatas biblioteca
Language:pt_BR
por
Published: 2010-09-27
Subjects:Quantificação genética, Raça nelore., Gado de Corte, Variação Genética.,
Online Access:http://www.alice.cnptia.embrapa.br/alice/handle/doc/862989
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Summary:Brazil has the second largest herd of cattle in the world (Anualpec (2008)) with predominance of Bos indicus breeds which have a higher heat tolerance, resistance to parasites and fertility than cattle of European origin. Interest in improving carcass and beef quality is growing in the National beef industry, pressured by the requirements of meat markets. The quantification of genetic variation and exploration of genomic segments that influence carcass and beef quality in the breeding population are essential for the establishment of quantitative and molecular criteria for selection. The PPARGC1A (peroxisome proliferative active receptor gamma coactivator 1 A), FABP4 (fatty acid binding protein 4) and IGF-1 (insulin-like growth factor) genes are candidates to influence production traits in cattle. Association of polymorphisms in these genes with production traits were reported but studies with the populations where marker assisted selection is to be applied are still necessary before this information can effectively be used by producers. The aim of this study was to investigate the presence of polymorphisms in the candidate genes PPARGC1A, FABP4 and IGF-1in reference families of Nellore cattle and relate them to meat production traits in these animals.

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