Reconstructing the whole mitochondrial DNA (mtDNA) from nuclear genome.
In several eukaryotic organisms, the nuclear genome has several partial copies of the mitochondrial DNA (mtDNA). These copies are called NUMTs (NUclear MiTochondrial DNA) and they have been known since 1967 when the first evidence of them were reported in the mouse nuclear genome. Despite almost fifty years have passed, the reason of their very existence remains controversial. However, their presence has been confirmed in an increasing number of genomes. The NUMts could be only another DNA idiosyncrasy, but they actually represent a serious issue for important application such as genome bar coding. There are many open questions about them.
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | Anais e Proceedings de eventos biblioteca |
| Language: | English eng |
| Published: |
2016-01-25
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| Subjects: | DNA mitocondrial, Genoma nuclear, Genoma, Genome, Nuclear genome, Mitochondrial DNA, |
| Online Access: | http://www.alice.cnptia.embrapa.br/alice/handle/doc/1035016 |
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| Summary: | In several eukaryotic organisms, the nuclear genome has several partial copies of the mitochondrial DNA (mtDNA). These copies are called NUMTs (NUclear MiTochondrial DNA) and they have been known since 1967 when the first evidence of them were reported in the mouse nuclear genome. Despite almost fifty years have passed, the reason of their very existence remains controversial. However, their presence has been confirmed in an increasing number of genomes. The NUMts could be only another DNA idiosyncrasy, but they actually represent a serious issue for important application such as genome bar coding. There are many open questions about them. |
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