The Biology of Germinal Centers in Lymphoid Tissue [electronic resource] /

This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.

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Bibliographic Details
Main Authors: Thorbecke, G. Jeanette. author., Tsiagbe, Vincent K. author., SpringerLink (Online service)
Format: Texto biblioteca
Language:eng
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1998
Subjects:Medicine., Cancer research., Immunology., Molecular biology., Oncology., Cell biology., Biomedicine., Cancer Research., Cell Biology., Molecular Medicine.,
Online Access:http://dx.doi.org/10.1007/978-3-662-13141-1
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Description
Summary:This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.