Cellular Peptidases in Immune Functions and Diseases [electronic resource] /

I: Membrane Peptidases in Immune Functions and Inflammation -- 1. Membrane Metalloendopeptidases in Immune Function and Disease -- 2. Structural Studies of Aminopeptidase P: A Novel Cellular Peptidase -- 3. Aminopeptidase P: A Cell-Surface Antigen of Endothelial and Lymphoid Cells -- 4. Human Lymphocyte X-Prolyl Aminopeptidase (Aminopeptidase P)-like Protein: A New Member of the Proline Peptidase Family? -- 5. Specific Inhibitors of Aminopeptidase P: Peptides and Pseudopeptides of 2-Hydroxy-3-Amino Acids -- 6. ?-Glutamyl Transpeptidase, a Blood-Brain Barrier Associated Membrane Protein: Splitting Peptides to Transport Amino Acids -- 7. Structure and Expression of Aminopeptidase N -- 8. Activation-Dependent Induction of T Cell Alanyl Aminopeptidase and Its Possible Involvement in T Cell Growth -- 9. Antisense-Mediated Inhibition of Aminopeptidase N (CD13) Markedly Decreases Growth Rates of Hematopoietic Tumour Cells -- 10. Co-Incubation of Lymphocytes with Fibroblast-like Synoviocytes and Other Cell Types Can Induce Lymphocytic Surface Expression of Aminopeptidase N/CD13 -- 11. Two Transfected Endothelial Cell Lines Expressing High Levels of Membrane Bound or Soluble Aminopeptidase N -- 12. Aminopeptidase N-Mediated Signal Transduction and Inhibition of Proliferation of Human Myeloid Cells -- 13. Regulation of Thymic Development by Neprilysin Inhibition -- 14. Proteases of Isolated Pancreatic Acinar Cells after Caerulein Hyperstimulation -- II: CD26/Dipeptidylpeptidase IV on Lymphocytes -- 15. Structure of CD26 (Dipeptidyl Peptidase IV) and Function in Human T Cell Activation -- 16. Molecular Associations Required for Signalling via Dipeptidyl Peptidase IV (CD26) -- 17. CD26/Dipeptidyl Peptidase IV in Lymphocyte Growth Regulation -- 18. CD26 Is Involved in Regulation of Cytokine Production in Natural Killer Cells -- 19. The Effect of Anti-CD26 Antibodies on DNA Synthesis and Cytokine Production (IL-2, IL-10 and IFN-?) Depends on Enzymatic Activity of DP IV/CD26 -- 20. New Fluorogenic Dipeptidyl Peptidase IV/CD26 Substrates and Inhibitors -- 21. Molecular Analyses of Human and Rat Dipeptidyl Peptidase IV -- 22. A Molecular Model of the Active Site of Dipeptidyl Peptidase IV: Explanation of the Substrate Specificity and Interaction with Inhibitors -- 23. The Level of CD26 Determines the Rate of HIV Entry in a CD4+ T-Cell Line -- 24. HIV-1 Envelope gp 120 and Viral Particles Block Adenosine Deaminase Binding to Human CD26 -- 25. Further Characterization of DPP IV-?, a Novel Cell Surface Expressed Protein with Dipeptidyl Peptidase Activity -- 26. Expression of Dipeptidylpeptidase IV (DPP IV/CD26) Activity on Human Myeloid and B Lineage Cells, and Cell Growth Suppression by the Inhibition of DPP IV Activity -- 27. CD26 as a Positive Regulator of HIV Envelope-Glycoprotein Induced Apoptosis in CD4+ T Cells -- 28. Comparative Study of CD26 as a Thl-like and CD30 as a Potential Th2-like Operational Marker in Leprosy -- III: Peptidases Involved in Cytokine Actions and in the Pathogenesis of Disease -- 29. Regulation of Neutrophil Activation by Proteolytic Processing of Platelet-Derived a-Chemokines -- 30. Selective Proteolytical Cleavage of the Ligand-Binding Chains of the IL-2-Receptor and IL-6-Receptor by Neutrophil-Derived Proteases -- 31. In Vitro Effects of ?-Glutamyltranspeptidase Inhibitor Acivicin on Human Myeloid and B Lineage Cells -- 32. Expression of Several Matrix Metalloproteinase Genes in Human Monocytic Cells -- 33. Lysosomal Cysteine Peptidases and Malignant Tumours -- 34. Expression of Cysteine Protease Inhibitors Stefin A, Stefin B, and Cystatin C in Human Lung Tumor Tissue -- 35. Contribution of the Proteasome to the a-Secretase Pathway in Alzheimer’s Disease -- 36. Dipeptidyl Peptidase IV (CD26) and Alzheimer Amyloid Protein Precursor (APP) in Polymyositìs -- 37, The HIV Protease and Therapies for AIDS -- 38. Leukodiapedesis, Function, and Physiological Role of Leucocyte Matrix Metalloproteinases -- 39. Matrix Metalloproteinases in Experimental Autoimmune Encephalomyelitis -- 40. Interaction of Transforming Growth Factor ß (TGFß) with Proteinase 3 -- 41. Liver Cysteine Proteinases in Macrophage Depression Induced by Gadolinium Chloride -- Contributors.

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Bibliographic Details
Main Authors: Ansorge, Siegfried. editor., Langner, Jürgen. editor., SpringerLink (Online service)
Format: Texto biblioteca
Language:eng
Published: Boston, MA : Springer US : Imprint: Springer, 1997
Subjects:Medicine., Immunology., Biochemistry., Biomedicine., Biochemistry, general.,
Online Access:http://dx.doi.org/10.1007/978-1-4757-9613-1
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Summary:I: Membrane Peptidases in Immune Functions and Inflammation -- 1. Membrane Metalloendopeptidases in Immune Function and Disease -- 2. Structural Studies of Aminopeptidase P: A Novel Cellular Peptidase -- 3. Aminopeptidase P: A Cell-Surface Antigen of Endothelial and Lymphoid Cells -- 4. Human Lymphocyte X-Prolyl Aminopeptidase (Aminopeptidase P)-like Protein: A New Member of the Proline Peptidase Family? -- 5. Specific Inhibitors of Aminopeptidase P: Peptides and Pseudopeptides of 2-Hydroxy-3-Amino Acids -- 6. ?-Glutamyl Transpeptidase, a Blood-Brain Barrier Associated Membrane Protein: Splitting Peptides to Transport Amino Acids -- 7. Structure and Expression of Aminopeptidase N -- 8. Activation-Dependent Induction of T Cell Alanyl Aminopeptidase and Its Possible Involvement in T Cell Growth -- 9. Antisense-Mediated Inhibition of Aminopeptidase N (CD13) Markedly Decreases Growth Rates of Hematopoietic Tumour Cells -- 10. Co-Incubation of Lymphocytes with Fibroblast-like Synoviocytes and Other Cell Types Can Induce Lymphocytic Surface Expression of Aminopeptidase N/CD13 -- 11. Two Transfected Endothelial Cell Lines Expressing High Levels of Membrane Bound or Soluble Aminopeptidase N -- 12. Aminopeptidase N-Mediated Signal Transduction and Inhibition of Proliferation of Human Myeloid Cells -- 13. Regulation of Thymic Development by Neprilysin Inhibition -- 14. Proteases of Isolated Pancreatic Acinar Cells after Caerulein Hyperstimulation -- II: CD26/Dipeptidylpeptidase IV on Lymphocytes -- 15. Structure of CD26 (Dipeptidyl Peptidase IV) and Function in Human T Cell Activation -- 16. Molecular Associations Required for Signalling via Dipeptidyl Peptidase IV (CD26) -- 17. CD26/Dipeptidyl Peptidase IV in Lymphocyte Growth Regulation -- 18. CD26 Is Involved in Regulation of Cytokine Production in Natural Killer Cells -- 19. The Effect of Anti-CD26 Antibodies on DNA Synthesis and Cytokine Production (IL-2, IL-10 and IFN-?) Depends on Enzymatic Activity of DP IV/CD26 -- 20. New Fluorogenic Dipeptidyl Peptidase IV/CD26 Substrates and Inhibitors -- 21. Molecular Analyses of Human and Rat Dipeptidyl Peptidase IV -- 22. A Molecular Model of the Active Site of Dipeptidyl Peptidase IV: Explanation of the Substrate Specificity and Interaction with Inhibitors -- 23. The Level of CD26 Determines the Rate of HIV Entry in a CD4+ T-Cell Line -- 24. HIV-1 Envelope gp 120 and Viral Particles Block Adenosine Deaminase Binding to Human CD26 -- 25. Further Characterization of DPP IV-?, a Novel Cell Surface Expressed Protein with Dipeptidyl Peptidase Activity -- 26. Expression of Dipeptidylpeptidase IV (DPP IV/CD26) Activity on Human Myeloid and B Lineage Cells, and Cell Growth Suppression by the Inhibition of DPP IV Activity -- 27. CD26 as a Positive Regulator of HIV Envelope-Glycoprotein Induced Apoptosis in CD4+ T Cells -- 28. Comparative Study of CD26 as a Thl-like and CD30 as a Potential Th2-like Operational Marker in Leprosy -- III: Peptidases Involved in Cytokine Actions and in the Pathogenesis of Disease -- 29. Regulation of Neutrophil Activation by Proteolytic Processing of Platelet-Derived a-Chemokines -- 30. Selective Proteolytical Cleavage of the Ligand-Binding Chains of the IL-2-Receptor and IL-6-Receptor by Neutrophil-Derived Proteases -- 31. In Vitro Effects of ?-Glutamyltranspeptidase Inhibitor Acivicin on Human Myeloid and B Lineage Cells -- 32. Expression of Several Matrix Metalloproteinase Genes in Human Monocytic Cells -- 33. Lysosomal Cysteine Peptidases and Malignant Tumours -- 34. Expression of Cysteine Protease Inhibitors Stefin A, Stefin B, and Cystatin C in Human Lung Tumor Tissue -- 35. Contribution of the Proteasome to the a-Secretase Pathway in Alzheimer’s Disease -- 36. Dipeptidyl Peptidase IV (CD26) and Alzheimer Amyloid Protein Precursor (APP) in Polymyositìs -- 37, The HIV Protease and Therapies for AIDS -- 38. Leukodiapedesis, Function, and Physiological Role of Leucocyte Matrix Metalloproteinases -- 39. Matrix Metalloproteinases in Experimental Autoimmune Encephalomyelitis -- 40. Interaction of Transforming Growth Factor ß (TGFß) with Proteinase 3 -- 41. Liver Cysteine Proteinases in Macrophage Depression Induced by Gadolinium Chloride -- Contributors.