Drug Absorption at Different Regions of the Human Gastro-Intestinal Tract: Methods of Investigation and Results / Arzneimittelabsorption aus verschiedenen Bereichen des Gastrointestinaltraktes beim Menschen: Untersuchungsmethoden und Ergebnisse [electronic resource] : Proceedings of an International Workshop on Methods in Clinical Pharmacology Frankfurt, November 14, 1986 / Vorträge und Diskussionen auf einem Internationalen Workshop „Methods in Clinical Pharmacology“ Frankfurt, 14. November 1986 /

Contents/Inhaltsverzeichnis -- Eröffnung und Themeneinführung -- Intubation techniques for the study of the absorption of drugs in man -- Simultaneous pharmacokinetic and in vivo gamma scintigraphic monitoring in the development of an enprofylline SR-tablet -- In Vivo Dissolution and Absorption Kinetics of Sustained -Release Theophylline, Studied with Stable Isotope Methodology -- Course of Development of the HF-capsule, variations and method related typical findings -- Evaluation of the colonic drug absorption in patients with an artificial intestinal stoma and by colonoscopy in normal volunteers -- Theophyllin. Absorption in verschiedenen Darmabschnitten -- Indication of Absorption of Theophylline from the Large Intestine following Administration of Depot Preparations -- Impaired Bioavailability of Theophylline Retard Preparations as a Result of pH-dependent Drug Release Rates -- Lokalisation der Absorption von Furosemid. Befunde und Folgerungen für verschiedene Darreichungsformen -- Absorption of Isosorbide-5-nitrate from the Gastrointestinal Tract -- Gastrointestinal Absorption of Drugs: Physico-chemical and biomathematical Aspects -- Absorption of Hexobarbital and Caffeine in Patients with liver cirrhosis -- Influence of Absorption Rate on the MetaboHc Kinetics of Theophylline -- Metabolism of Fosfestrol by intestinal mucosa -- Drug input rate from the Gl-tract, Michaelis-Menten kinetics and the bioavailability of Slow-Release Verapamil and Nifedipine -- Absorption of Caffeine in Patients with Gastric Stasis and after partial gastrectomy (BILLROTH II) -- Round table-discussion -- Schlußwort.

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Bibliographic Details
Main Authors: Rietbrock, Norbert. editor., Woodcock, Barry G. editor., Staib, A. Horst. editor., Loew, Dieter. editor., SpringerLink (Online service)
Format: Texto biblioteca
Language:eng
Published: Wiesbaden : Vieweg+Teubner Verlag : Imprint: Vieweg+Teubner Verlag, 1987
Subjects:Medicine., Gastroenterology., Medicine & Public Health., Medicine/Public Health, general.,
Online Access:http://dx.doi.org/10.1007/978-3-322-91091-2
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Summary:Contents/Inhaltsverzeichnis -- Eröffnung und Themeneinführung -- Intubation techniques for the study of the absorption of drugs in man -- Simultaneous pharmacokinetic and in vivo gamma scintigraphic monitoring in the development of an enprofylline SR-tablet -- In Vivo Dissolution and Absorption Kinetics of Sustained -Release Theophylline, Studied with Stable Isotope Methodology -- Course of Development of the HF-capsule, variations and method related typical findings -- Evaluation of the colonic drug absorption in patients with an artificial intestinal stoma and by colonoscopy in normal volunteers -- Theophyllin. Absorption in verschiedenen Darmabschnitten -- Indication of Absorption of Theophylline from the Large Intestine following Administration of Depot Preparations -- Impaired Bioavailability of Theophylline Retard Preparations as a Result of pH-dependent Drug Release Rates -- Lokalisation der Absorption von Furosemid. Befunde und Folgerungen für verschiedene Darreichungsformen -- Absorption of Isosorbide-5-nitrate from the Gastrointestinal Tract -- Gastrointestinal Absorption of Drugs: Physico-chemical and biomathematical Aspects -- Absorption of Hexobarbital and Caffeine in Patients with liver cirrhosis -- Influence of Absorption Rate on the MetaboHc Kinetics of Theophylline -- Metabolism of Fosfestrol by intestinal mucosa -- Drug input rate from the Gl-tract, Michaelis-Menten kinetics and the bioavailability of Slow-Release Verapamil and Nifedipine -- Absorption of Caffeine in Patients with Gastric Stasis and after partial gastrectomy (BILLROTH II) -- Round table-discussion -- Schlußwort.