Canine transmissible venereal tumor of atypical presentation

An 8 years old, intact male, boxer was presented at the Santo Tomas Veterinary Teaching Hospital because of a volume increase in his right eye of 2 months of duration; which didn´t respond to oral prednisone (0,7 mg/kg, BID), or dexamethasone and tobramycin in ophthalmic ointment (1 drop, TID). On physical exam, a mass in the third eyelid and another on the base of the penis were noted. Cytology of the mass near the genital area showed cells compatible with transmissible venereal tumor (TVT). Besides that, ocular ultrasonography showed an irregular mass with neoplastic characteristics in the medial area of the eyeball and abdominal ultrasound indicated a mass dorsal to the bladder. Fine needle aspiration of the eye and abdomen masses were done under sedation; cytology of the tumor in the abdomen indicated TVT and in the eye the results were suppurative inflammation, necrosis and epithelial dysplasia. Neoplasia couldn´t  be rule out or confirmed. Initial treatment included vincristine (8 cycles, 0,7 mg/m²) obtaining a parcial remission; so considering a possible resistance of the cells to this drug, doxorrubicin (30 mg/m²) was used. The patient had a positive response to doxorrubicin achieving complete remission with a single aplication.

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Bibliographic Details
Main Authors: Crossley, Rodrigo, Ramírez, Johana Alejandra
Format: Digital revista
Language:spa
Published: Universidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina Veterinaria y de Zootecnia 2017
Online Access:https://revistas.unal.edu.co/index.php/remevez/article/view/68695
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